Up in Smoke is the soundtrack/comedy album tied to the 1978 film Up in Smoke starring Cheech Marin and Tommy Chong. Released in late 1978, it blends songs, comedy sketches, dialogue excerpts, and sound bites from the movie into a single listening experience. The album captures the duo's trademark counterculture humor, centered on the misadventures of two laid-back cannabis enthusiasts. Rather than being a conventional music album, it's a hybrid of soundtrack and comedy record, with musical numbers interwoven with scenes from the film. Notable tracks include "Up in Smoke", "Framed", "Earache My Eye", and "Lost Due to Incompetence (Theme for a Big Green Van)."

- Disc 1 -
The Finkelstein Shit Kid - By Mr. Stoner
Up in Smoke
Low Rider - By War
1st Gear, 2nd Gear - By Pedro & Man
Framed
Searchin' - By Search Boys
The Ajax Lady - By Man & the Ajax Lady
Strawberry's - By Yesca
- Disc 2 -
Here Come the Mounties to the Rescue - By Yesca
Sometimes When You Gotta Go, You Can't - By Pedro & SGT. Stedenko
Lost Due to Incompetence (Theme for a Big Green Van) - By Yesca
Lard Ass - By Pedro, Man, Officer Clyde & SGT. Stedenko
Rock Fight
I Didn't Know Your Name Was Alex - By Man, Jade East & Pedro
Earache My Eye - By Alice Bowie
Up in Smoke (Reprise)